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目的调查分析一起家庭聚集性布病疫情,探讨该起疫情发生的原因和可能的传播途径,为疫情防控提供参考。方法对患儿及其家庭密切接触者开展流行病学调查,对调查结果、实验室检测结果进行描述性流行病学分析。结果本次疫情共有2例实验室确诊布病病例。采集患儿及其4名家庭密切接触者血液样本和患儿母亲的乳汁1份,患儿及其母亲血液样本虎红平板凝集实验(RBPT)和试管凝集试验(SAT)检测为阳性,分离到2株羊种2型布鲁氏菌;1份乳汁和其他血液样本未检出阳性结果。结论现场流行病学资料结合实验室结果支持是一起可疑实验室获得性感染引起母婴发病的家庭聚集性布病疫情,羊2型布鲁氏菌是疫情的致病原,实验室不规范操作是可疑暴露。应强化生物安全意识,落实防护措施。
Objective To investigate and analyze the incidence of brucellosis with family aggregation in China, discuss the causes of the outbreak and the possible routes of transmission, and provide reference for prevention and control of epidemic situation. Methods To carry out epidemiological investigation on the close contacts of children and their families, and to carry out descriptive epidemiological analysis of the survey results and laboratory test results. Results A total of 2 cases of brucellosis were confirmed in this epidemic. A total of 1 blood sample was collected from children and their close relatives in 4 families and their mothers ’mothers. RBPT and SAT were positive in children and their mothers’ blood samples. 2 strains of Brucella brucei type 2; 1 milk and other blood samples did not detect positive results. Conclusions The epidemiological data from the field combined with the support of laboratory results is a familial epidemic of brucellosis that causes mother-infant incidence in suspected laboratory-acquired infections. Brucella spp. Of sheep is the causative agent of the outbreak and the laboratory does not regulate the operation Is suspicious exposure. We should strengthen the awareness of biosafety and implement protective measures.