论文部分内容阅读
目的探讨人食管鳞癌组织中的淋巴管生成及其与淋巴结转移的临床意义。方法采用酶组织化学法,检测49例食管鳞癌、癌旁及切端正常食管上皮组织中淋巴管的生成及定位特征,并应用图像分析方法测定淋巴管数量和阳性单位、及其与淋巴结癌转移的关系。结果肿瘤组织中淋巴管生成和阳性单位均与淋巴结转移密切相关(P<0.01),癌旁组织中淋巴管密度高于癌组织(P<0.01),酶组织化学法可较好地显示食管鳞癌组织中的淋巴管。结论食管鳞癌的淋巴管形成与淋巴结转移相关,为肿瘤细胞淋巴道转移提供了条件。
Objective To investigate the clinical significance of lymphangiogenesis and lymph node metastasis in human esophageal squamous cell carcinoma. Methods Enzymatic histochemistry was used to detect the formation and localization of lymphatic vessels in 49 cases of esophageal squamous cell carcinoma, paracancer and normal esophageal epithelium. Image analysis was used to determine the number of lymphatic vessels and their positive units. relationship. Results The lymphangiogenesis and positive units in tumor tissues were closely related to the lymph node metastasis (P <0.01), and the lymphatic vessel density in paracancerous tissues was higher than that in cancer tissues (P <0.01). Enzyme histochemical method could well display esophageal squamous cell carcinoma Lymphatic vessels in cancer tissue. Conclusion The formation of lymphangiogenesis in esophageal squamous cell carcinoma is related to lymph node metastasis, which provides the conditions for lymphatic metastasis of esophageal squamous cell carcinoma.