目的探讨肺表面活性物质(PS)在治疗早产儿肺透明膜病(HMD)的临床护理疗效。方法将肺表面活性物质固尔苏药液200 mg/kg通过气管插管及导管分4次注入气管内,并通过正压通气使之均匀分布于两肺气道。结果观察患儿用药前后呼吸机参数的变化。10例患儿中,8例痊愈出院,1例好转出院,1例在HMD痊愈后发生败血症、硬肿症(新生儿寒冷损伤综合征)、感染性休克而死亡。结论应用PS治疗HMD后,对症的护理可明显改善其转归。 Objective To investigate the clinical effects of pulmonary surfactant (PS) in the treatment of hyaline membrane disease (HMD) in preterm infants. Methods 200 mg / kg of cefuroxime axetil was infused into the trachea via tracheal intubation and catheter four times and evenly distributed in the two lung airways by positive pressure ventilation. Results The changes of ventilator parameters before and after treatment were observed. Of the 10 children, 8 were discharged, one was discharged, one was septic, scleredema (neonatal cold injury syndrome), septic shock and death after HMD was healed. Conclusion After treatment of HMD with PS, symptomatic care can significantly improve its outcome.