论文部分内容阅读
①目的探讨降纤酶对急性脑梗死病人的治疗作用。②方法对５０例急性脑梗死病人（治疗组）行降纤酶治疗，分别观察治疗前后血浆凝血因子Ⅰ（Ｆｇ）、凝血因子Ⅱ时间（ＰＴ）、血液流变学及脑电地形图的变化，并与４６例应用维脑路通和７０６代血浆治疗的对照组进行比较。③结果降纤酶治疗后，Ｆｇ明显降低，ＰＴ明显延长，与治疗前比较差异有显著性（ｔ＝３．９２～４．９８，Ｐ＜０．０５，０．０１）。治疗组全血黏度和脑电地形图各波段功率值较治疗前和对照组治疗后明显下降（ｔ＝２．８８～１９．５３，Ｐ＜０．０１）。神经功能缺损和生活能力评分较治疗前明显降低（ｔ＝３．７６～１２．５５，Ｐ＜０．０１）。④结论降纤酶对急性脑梗死具有一定的治疗作用。
①Objective To investigate the therapeutic effect of defibrase on patients with acute cerebral infarction. Methods Fifty patients with acute cerebral infarction (treatment group) were treated with defibrase. The change of plasma coagulation factor Ⅰ (Fg), coagulation factor Ⅱ (PT), hemorheology and electroencephalogram were observed before and after treatment. And compared with 46 control subjects treated with Venoruton and 706 generations of plasma. Results After defibrase treatment, Fg was significantly reduced, PT was significantly prolonged, compared with the pre-treatment difference was significant (t = 3.92 ~ 4.98, P <0.05,0.01). In the treatment group, the whole blood viscosity and the EEG power of each band were significantly decreased (t = 2.88 ~ 19.53, P <0.01) after treatment compared with before treatment and control group. Neurological impairment and viability scores were significantly lower than before treatment (t = 3.76 ~ 12.55, P <0.01). ④ Conclusion defibrase on acute cerebral infarction has a certain therapeutic effect.