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肺纤维化的传统治疗效果差且不良反应多。甘草甜素具有抗炎、免疫调节和抗氧化等作用,我们观察了甘草甜素对不同时相大鼠肺纤维化模型的干预作用及对肺组织转化生长因子(TCF)-β_1表达的影响,旨在为临床治疗提供新的思路。
Traditional treatment of pulmonary fibrosis has poor efficacy and many adverse reactions. Glycyrrhizin has anti-inflammatory, immunomodulatory and anti-oxidative effects. We observed the effects of glycyrrhizin on rat pulmonary fibrosis at different phases and the effect on the expression of transforming growth factor (TCF)-β_1 in lung tissue. It aims to provide new ideas for clinical treatment.