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目的掌握手足口病重症病例的流行特征,分析普通病例转成重症病例的早期危险因素。方法采用病例对照研究,对2010年龙岩市手足口病重症病例进行流行特征及高危因素分析。结果重症病例以1~3岁为主,夏季多发;单因素分析:就诊不及时、神经系统症状、消化和呼吸系统症状,EV71阳性等为主要高危因素;多因素分析:神经系统症状、EV71阳性、家庭人口密集为高危因素。结论对早期出现神经系统症状、实验室检查EV71阳性、家庭人口密集的低年龄组手足口病患儿,应结合临床症状予以重点关注。
Objective To grasp the epidemiological characteristics of HFMD cases and to analyze the early risk factors of common cases into severe cases. Methods A case-control study was conducted to analyze the prevalence and risk factors of HFMD in Longyan in 2010. Results The main cases of severe cases were 1 to 3 years old and multiple cases in summer. Univariate analysis showed that neurological symptoms, digestive and respiratory symptoms and EV71 positive were the main risk factors when the symptoms were not treated. Multivariate analysis showed that neurological symptoms, EV71 positive The family population is high risk. Conclusions Children with hand-foot-mouth disease in low age group with early neurological symptom, laboratory positive EV71, and dense family population should pay special attention to the clinical symptoms.