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目的探讨黄体酮联合曲马多、山莨菪碱治疗肾绞痛的临床效果。方法选取2011年9月—2013年12月中山市南区医院收治的肾绞痛患者100例,将患者按随机抽签法分为治疗组与对照组,各50例。对照组给予曲马多联合山莨菪碱治疗,治疗组在此基础上加用黄体酮治疗。比较两组患者的临床疗效及不良反应发生率。结果治疗组总有效率(98.0%)高于对照组(88.0%),差异有统计学意义(P<0.05)。治疗组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论黄体酮联合曲马多、山莨菪碱治疗肾绞痛能有效提高治疗效果,不良反应小。
Objective To investigate the clinical effect of progesterone combined with tramadol and anisodamine on renal colic. Methods From September 2011 to December 2013, 100 patients with renal colic were enrolled in Zhongshan District Southern District Hospital. The patients were randomly divided into treatment group and control group, with 50 cases in each group. The control group was treated with tramadol combined with anisodamine, and the treatment group was treated with progesterone on the basis of this. The clinical efficacy and incidence of adverse reactions in both groups were compared. Results The total effective rate (98.0%) in the treatment group was higher than that in the control group (88.0%), the difference was statistically significant (P <0.05). The incidence of adverse reactions in the treatment group was lower than that in the control group, the difference was statistically significant (P <0.05). Conclusions Progesterone combined with tramadol and anisodamine in treatment of renal colic can effectively improve the therapeutic effect with little adverse reaction.