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β-阻滞剂由于增加老年人心衰的发生率,故用于治疗老年高血压患者仍有争议。作者为了弄清老年人对β-阻滞剂的耐受性,尤其对心衰的影响,选择65岁以上高血压患者301例在门诊观察治疗,其中65～69岁217例,70～74岁58例,75岁以上26例。42例(14%)单用β-阻滞剂;51例(17%)单用利尿剂;193例(64%)用β-阻滞剂和利尿剂或其它药物联合治疗;15例(5%)未治。采用最常用的2种β-阻滞剂为心得安和甲氧乙心安(metoprolol),平均剂量分别为252mg/d 和189mg/d。结果均能有效地控制血压:65～69岁组控制在156/91mmHg,70～74岁组
Beta-blockers are still controversial for the treatment of elderly hypertensive patients because they increase the incidence of heart failure in the elderly. In order to understand the elderly tolerance of β-blockers, especially on the impact of heart failure, select over 301 hypertensive patients over the age of 65 in the out-patient observation and treatment, of which 65 to 69 years in 217 cases, 70 to 74 years 58 cases, 26 cases over 75 years old. Forty-two patients (14%) received β-blocker alone; 51 (17%) had diuretics alone; 193 (64%) were treated with β-blockers and diuretics or other drugs; %) Not treated. The two most commonly used beta-blockers were propranolol and metoprolol, with mean doses of 252 mg / day and 189 mg / day, respectively. The results can be effective in controlling blood pressure: 65 to 69-year-old control in 156 / 91mmHg, 70 to 74-year-old group