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十九世纪曾认为所有的结肠炎都是感染性疾病。1932年Crohn叙述了末端回肠炎。直到1960年才把溃疡性结肠炎和结肠克隆病区别开来。因而,大大加深了我们对这两种疾病的认识。 一、流行病学 溃疡性结肠炎 克隆病 发病率 病例/10万人 2～6 1～5 流行情况 病例/10万人 40～80 10～50 第二次世界大战后,克隆病的发病率逐年增加,原因不清,这可能与诊断水平不断提高有关。并且提出了一些学说包括婴儿的母乳喂养减少或婴儿胃肠炎发病率改变等。在某些地区,该病较常见,在苏格兰和瑞典发病率趋于平稳,甚至减少。然而这种病在一些罕见的国家如日本和印度,其患者人数明显增多,这与采用西方的生活方式有关。
Nineteenth Century that all colitis are infectious diseases. 1932 Crohn recounts terminal ileitis. It was not until 1960 that the distinction between ulcerative colitis and colon disease was distinguished. Thus, we have greatly deepened our understanding of these two diseases. Epidemiology Crohn’s disease incidence of ulcerative colitis per 100,000 people 2 ~ 6 1 ~ 5 Prevalence cases / 100,000 people 40 ~ 80 10 ~ 50 After the Second World War, the incidence of Crohn’s disease year after year Increase, the reason is unclear, this may be related to the continuous improvement of diagnostic level. And put forward some doctrines, including the reduction of infant breastfeeding or the incidence of infant gastroenteritis and so on. In some areas, the disease is more common and morbidity in Scotland and Sweden tends to be steady or even reduced. However, in some rare countries such as Japan and India, the disease has seen a marked increase in the number of patients, which is related to the adoption of Western lifestyles.