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目的 分析内蒙古自治区疑似预防接种异常反应(AEFI)管理工作现状及存在问题,提出下一步工作策略.方法 采用SWOT分析法对内蒙古自治区AEFI现有工作进行综合分析.结果 内蒙古自治区AEFI管理水平不断提高,AEFI报告数由2009年的213例增加到2015年的2 381例,监测系统灵敏度逐步提高,但面临经费缺乏、人员老化和补偿困难的问题,如45岁以上工作人员占50％以上,且无专职从事AEFI人员.结论 通过开展疫苗临床试验、疫苗国家监管体系职能评估(NRA评估)和争取政府支持,并且充分利用媒体扩大宣传效果,积极采取有利措施,可进一步提高内蒙古自治区AEFI管理水平.“,”Objective To analyze the present situation of AEFI work and the problems existed in which,put forward following strategies.Methods The AEFI work in Inner Mongolia autonomous region was analyzed synthetically by SWOT analysis.Results The results of AEFI management are better and better,and the observation system become more and more sensitive in Inner Mongolia autonomous region,AEFI case number increased from 213 in 2009 to 2 381 in 2015.However,expenditure deficiency,the aging of staff,being difficulty to compensate exist in AEFI work,half of the staff in centers for disease control and prevention in Inner Mongolia autonomous region are older than 45,and none work wholly in AEFI field.The management level of AEFI can be improved by carrying out vaccine clinical trial,NRA assessment,striving for government support,utilizing media adequately and expanding publicity in Inner Mongolia autonomous region.Conclusion It is necessary to utilize the present condition adequately and to search effective solutions,in order to promote the AEFI work quanlity in Inner Mongolia gradually.