The pressure fluctuation in the flow passage of both impeller and casing is addressed on design condition. The initial conditions for the unsteady turbulent simulation are resulted from the steady calculations, and the three dimensional unsteady turbulent simulation concerning the rotor-stator interaction is executed by a Navier-Stoke solver embedded with k -ε turbulence model and with appropriate moving interface boundary conditions. Detecting points are distributed in the flow passage in different radial and circumferential positions to capture the static pressure fluctuation character for one cycle of the impeller. The time-domain spectrums show that the static pressure curves are periodic and have five peaks and five valleys. With the radius increasing, the pressure fluctuation peak-to-peak values in the impeller are increasing, and reach the maximum value on the interface. In the casing flow passage, those values are about 7% of local static pressure except some ones near the tongue. The values become decreasingly in the diffuser pipe. The frequency spectrums transformed by fast Fourier transform (FFT) show that the dominant frequency is approximate with the blade passing frequency, and the pressure fluctuations in impeller passage have high frequency content while those in casing ones have no such information.