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目的：观察血浆提取物－－浓缩生长因子（CGF）在牙缺失伴骨缺损种植修复中应用的临床效果。方法：选择口内牙齿缺失伴骨缺损病人30例，种植手术中应用CGF技术配合植骨成功植入NobelReplace等常用牙种植体63枚。3～4个月后行二期手术及上部结构修复，随访2～5年，观察种植体稳定性、骨结合情况及种植体周围骨量与软组织形态变化情况。结果：本组病例修复后随访期内，种植体骨结合情况良好，存留率100％。骨增量效果理想，软组织形态正常，病人满意度良好。结论：CGF技术应用于口腔种植手术，可以明显缩短植入骨粉成骨时间，有较好的骨增量效果，且术中病人痛苦较小、易被接受，适应证广泛，是牙缺失伴骨缺损患者种植修复中较好的辅助手段之一。“,”Objective To observe the clinical ef ects of Concentrate Growth Factors technique in the dental implant restoration.Methods 30 patients were retrospectively reviewed.63 No-belReplace etc dental implants were implanted.Al of the surgical are used Concentrate Growth Factors.After 3-4 months,the upper part of the defect was restored.Stability of the implant,im-plant osseointegration and soft tissue quality were evaluated in 2-5 years after treatments.Results In the fol ow-up period,al the implants were obtained good osseointegration.The success rate was 100%.Patients were satisfied with these treatments.Conclusion The Concentrate Growth Factors technique is a good method to repair dentition defect.