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Objective:To study the main clinical and histopathological features of 12 patients with Hodgkin’s lymphoma (HL) diagnosed primarily from bone marrow (BM) involvement. n
Methods:We included 12 acquired immunodeficiency syndrome (AIDS) patients with HL assisted in the F. J. Mu?iz Infectious Diseases Hospital since January 2002 to December 2013. hTe diagnosis of HL with primary BM involvement in patients was conifrmed by clinical, histopathological, and immunohistochemical ifndings. n
Results:All patients presented“B”symptoms and pancytopenia. All of them had stage IV neoplasm disease because of BM inifltration. hTe median of CD4+T-cell counts was 114 cells/μL, and mixed cellularity (MC) was the most frequent histopathological subtype of 92%cases.
Conclusion:When other causes are excluded, BM biopsy should be performed in AIDS patients with“B”symptoms and pancytopenia to evaluate BM inifltration by atypical lymphocytes.
Methods:We included 12 acquired immunodeficiency syndrome (AIDS) patients with HL assisted in the F. J. Mu?iz Infectious Diseases Hospital since January 2002 to December 2013. hTe diagnosis of HL with primary BM involvement in patients was conifrmed by clinical, histopathological, and immunohistochemical ifndings. n
Results:All patients presented“B”symptoms and pancytopenia. All of them had stage IV neoplasm disease because of BM inifltration. hTe median of CD4+T-cell counts was 114 cells/μL, and mixed cellularity (MC) was the most frequent histopathological subtype of 92%cases.
Conclusion:When other causes are excluded, BM biopsy should be performed in AIDS patients with“B”symptoms and pancytopenia to evaluate BM inifltration by atypical lymphocytes.