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目的了解深圳市龙岗区手足口病暴发疫情流行特征,为采取有效的干预措施提供科学依据。方法收集国家疾病报告信息管理系统和深圳市疾病控制信息管理系统中相关的手足口病疫情监测资料进行综合分析。结果 2005年1月～2009年6月,深圳市龙岗区共发生手足口病暴发疫情22起(报告病例180例),占全区暴发疫情总数的12.29%;以托幼机构暴发为主(81.82%);疫情暴发高峰为3～6月(81.82%);2005-2006年手足口病暴发阳性标本均为Cox-A16型(10/10,100.00%),而2008-2009年则以EV71型为主(32/50,64.00%);暴发疫情的持续时间与疫情的非及时处理(r=0.482,P=0.023)及暴发疫情的发病人数(r=0.640,P=0.001)呈显著性正相关;在控制发病人数的影响之后,疫情持续时间与疫情非及时处理的相关性明显增强(r=0.765,P<0.001);暴发疫情每延迟处理1.14 d或发病人数每增加1.31人,疫情持续时间均会延长1 d:y=-7.16+1.14 x1+1.31 x2。结论近年深圳市龙岗区手足口病暴发疫情显著增多,托幼机构是疫情暴发的主要场所,而及时处置则是暴发疫情控制的关键。
Objective To understand the epidemiological characteristics of HFMD in Longgang District of Shenzhen City and provide a scientific basis for effective intervention. Methods Collecting the national disease reporting information management system and Shenzhen disease control information management system related to hand, foot and mouth disease surveillance data for a comprehensive analysis. Results From January 2005 to June 2009, 22 outbreaks of hand-foot-mouth disease (180 reported cases) occurred in Longgang District of Shenzhen City, accounting for 12.29% of the total number of outbreaks in the district; mainly outbreaks of child-care institutions (81.82 %). The outbreak peak ranged from March to June (81.82%). Cox-A16 positive cases (10/10, 100.00%) were found in HFMD cases in 2005-2006, while in EV71 cases in 2008-2009 (32/50, 64.00%). The duration of the outbreak was significantly and positively correlated with the outbreak time (r = 0.482, P = 0.023) and the number of outbreaks (r = 0.640, After controlling the number of affected persons, the correlation between the duration of the outbreak and the non-timely treatment of the outbreak was significantly enhanced (r = 0.765, P <0.001). The duration of the outbreak was 1.14 days Will extend 1 d: y = -7.16 + 1.14 x1 + 1.31 x2. Conclusion In recent years, the outbreak of HFMD in Longgang District of Shenzhen City increased significantly. The nursery-child care organization was the main site of the outbreak of epidemic situation, and the timely disposal was the key to outbreak control.