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在意大利的乙型肝炎表面抗原携带者中发现一个新的抗原抗体系统即δ抗原抗体系统。对HBsAg(-)227例和HBsAg(+)510例的血清测定抗δ。227例HBsAg(-)者中对照者52名,急性非乙型肝炎61例,慢性非乙型肝炎64例,非肝脏疾病50例。HBsAg(+)患者中慢性肝病241例;无症状携带者134例;急性乙型肝炎135例。 52例正常对照者和175例HBsAg(-)的急性或慢性肝脏病者血清抗δ皆(-)。不同区域各种HBsAg(+)患者抗δ的发生率见附表。HBsAg(+)510例血清中70例抗δ(+)。三个国家的血清中皆有抗δ。20例抗δ(+)意大利患者中17例为HBsAg/ay,3例为HBsAg/ad。抗δ(+)的2例日本患者皆为HBsAg/ad。慢性肝病患者抗δ的阳性率显著高于HBsAg携
In Italy, hepatitis B surface antigen carriers found a new antigen antibody system that is the δ antigen antibody system. Serum levels of 227 HBsAg (-) and 510 HBsAg (+) were determined for anti-δ. Among 227 HBsAg - positive controls, 52 were controls, 61 with acute non - hepatitis B, 64 with chronic non - hepatitis B, and 50 with non - liver disease. 241 cases of chronic liver disease in HBsAg (+) patients, 134 cases of asymptomatic carriers and 135 cases of acute hepatitis B patients. Serum anti-delta (-) was detected in 52 healthy controls and 175 HBsAg-negative patients with acute or chronic liver disease. The incidence of anti-δ in various HBsAg (+) patients in different regions is tabulated. Seventy patients with HBsAg (+) 510 serum anti-δ (+). Serum in all three countries has anti-δ. Seventeen of 20 anti-δ (+) Italian patients were HBsAg / ay and 3 were HBsAg / ad. Two Japanese patients with anti-δ (+) were all HBsAg / ad. The positive rate of anti-δ in patients with chronic liver disease was significantly higher than that of HBsAg carriers