中枢抑制药、全麻药对局麻药作用的影响已被大家熟知。本文介绍下列几方面的影响因素,供临床用药参考。 一、病理状态 (一)局部炎症 急性炎症期拔牙和髓病治疗时,临床观察利多卡因的麻醉效果明显优于普鲁卡因。据统计,急性炎症期拔牙,利多卡因无痛率达85.2％,而普鲁卡因无痛率只有32.1％。 急性牙髓炎摘髓或开髓术中,二者麻 Central inhibitory drugs, anesthetics on the role of local anesthetic effects have been well known. This article describes the following aspects of the factors for clinical reference. First, the pathological state (A) local inflammation acute inflammation of the extraction and myelopathy treatment, the clinical observation of lidocaine anesthesia was significantly better than procaine. According to statistics, the acute inflammation of tooth extraction, lidocaine painless rate of 85.2%, while procaine painless rate was only 32.1%. Acute pulpitis pulp or open pulp surgery, both Ma