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沙立度胺 (thalidom ide,塔里陀迈 ,反应停 ,酞胺哌啶酮 ) 5 0年代后期用作镇静剂 ,由于治疗妊娠呕吐造成数以万计的海豹肢体等畸形儿 ,196 1年从市场上撤出。以后临床报道沙立度胺治疗红斑结节性麻风病有效 ;近年来国外用沙立度胺治疗一些临床棘手的疾病 :如白塞氏病、克隆氏病和人免疫缺陷病毒 (HIV)感染引起的口疮性口炎等取得了较好的疗效。为此 ,特将此综述请天津医科大学总医院药剂科叶立副主任药师予以节译以飨读者。
Thalidomide (thalidomide, thalidomide, thalidomide, thalidomide) was used as a sedative in the late 1950s due to the treatment of pregnancy vomiting caused by tens of thousands of seals and other deformed limbs, 196 from Withdraw from the market Later clinical reports thalidomide treatment of erythema nodosum leprosy effective; in recent years with thalidomide treatment of some of the clinical thorny diseases: such as Behcet’s disease, Crohn’s disease and human immunodeficiency virus (HIV) infection caused Aphthous stomatitis and achieved a good effect. To this end, especially this review, please Tianjin Medical University General Hospital Pharmacy Ye Li, deputy director of pharmacists to interpret to readers.