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目的通过对依沙吖啶配伍米非司酮用于中期妊娠引产的临床研究。方法观察组第1天上午空腹或进食后2小时顿服米非司酮lOOmg,同时常规行依沙吖啶lOOmg羊腹腔内注射引产,第2天上午空腹或进食后2小时顿服米非司酮lOOmg.对照组依沙吖啶用法用量同观察组,不加用米非司酮。结果观察组148例(98.6%)自然排胎,2例因宫缩欠佳行催产素等5U靜脉滴注诱发宫缩,引产成功率为98.6%;对照组120例(80%)自然排胎,30例因宫颈成熱条件差或宫缩欠佳行催产素5U靜脉滴注,其中21例自然排胎,9例行钳刮术结束分娩,引产成功率80%,引产成功率比较差异有显著性意义(P<0.05)。
Objective To study the clinical efficacy of ethacridine in combination with mifepristone for induction of labor during the second trimester pregnancy. Methods The observation group on the first day morning fasting or 2 hours after eating meal mifepristone lOOmg, while regular line of acridine lOOmg sheep intraperitoneal injection of induction of labor, fasting on the second day or 2 hours after eating meal Dayton Division Ketone lOOmg. The control group according to the amount of acridine use the same amount of observation group, without adding mifepristone. Results In the observation group, 148 cases (98.6%) were naturally discharged and 2 cases received contractions due to uterine contractions such as oxytocin. The success rate of induced labor was 98.6%. In the control group, 120 cases (80%) were naturally discharged , 30 cases due to poor thermal conditions or cervical uterine contractions oxytocin 5U intravenous infusion, of which 21 cases of natural row of tires, 9 cases of clamp curettage end of delivery, the success rate of induction of labor was 80%, the success rate of induced labor compared with the difference Significant significance (P <0.05).