抗组织胺药Mequitazine(LM-209)治疗变应性鼻病的临床效果

来源 :国外医学.耳鼻咽喉科学分册 | 被引量 : 0次 | 上传用户:xxj8880430
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LM-209是硫氮蒽的衍生物,其化学结构式为: 每日早餐后和睡前各服1片,连服7天为一疗程。作者们选择了具有打喷嚏、水样鼻涕和鼻阻塞等典型症状及鼻内检查诊断为变应性鼻炎的患者作为观察对象,并用抗原提取液作皮内反应。用嗜伊红染色检查鼻涕中嗜酸细胞。比较给药前后鼻症状及鼻局部检查所见,综合判断LM-209的疗效。按医师判断:显效占9.6%,有效47.4%,稍有效19.3%,无效22.2%,恶化1.5%。总有 LM-209 is a derivative of diazepam, its chemical formula is: daily breakfast and before going to bed one each, even for 7 days for a course of treatment. The authors selected patients with typical symptoms of sneezing, watery nose, and nasal obstruction, as well as patients diagnosed as allergic rhinitis by intranasal examination, and used an antigen extract for intradermal reactions. Eosin staining to check for nasal eosinophils. Before and after administration of nasal symptoms and nasal examination found, a comprehensive assessment of the efficacy of LM-209. Judge by the doctor: effective accounted for 9.6%, effective 47.4%, 19.3% slightly effective, ineffective 22.2%, 1.5% worse. always
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