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The selective catalytic reduction (SCR) of NOx by NH3 is one of the most mature technologies for NOx treatment. Catalysts are the main factors affecting denitrification efficiency. Zeolites as low-temperature NH3-SCR catalysts have been extensively studied in the past few years. In this work, the mechanism of zeolites for NH3-SCR reaction was reviewed and the denitrification performances of zeolite catalysts prepared by different methods were compared. The effects of sulfur and water poisoning on zeolite catalysts in NH3-SCR reaction were also analyzed. Several ways to address the problems in low-temperature NH3-SCR reaction were discussed. Hopefully, this review could provide a fundamental understanding of SCR reaction on zeolite catalysts and pave the way toward similar studies to realize its commercial applications.