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目的探计头孢哌酮舒巴坦在老年性肺炎患者中的疗效及对血清CRP、ALB、PCT、MIF、D-D的影响。方法回顾性分析我院收治的62例老年肺炎患者的临床资料,根据治疗方法的不同分为治疗组和对照组各31例,其中对照组患者静脉滴注头孢他啶,治疗组患者静脉滴注头孢哌酮舒巴坦,比较两组患者的临床疗效和治疗前后血清CRP、ALB、PCT、MIF、D-D水平。结果治疗组患者的总有效率为93.55%,显著高于对照组患者的总有效率80.66%,P<0.05;治疗前两组患者的CRP、ALB、PCT、MIF、D-D水平差异均无统计学意义(P>0.05);治疗后两组患者的CRP、ALB、PCT、MIF、D-D均显著低于治疗前,且治疗组均显著低于对照组,P<0.05。结论采用头孢哌酮舒巴坦治疗老年性肺炎快速降低患者血清的炎症指标,临床疗效显著。
Objective To investigate the efficacy of cefoperazone sulbactam in patients with senile pneumonia and its effect on serum CRP, ALB, PCT, MIF and D-D. Methods Retrospective analysis of 62 cases of elderly patients with pneumonia admitted to our hospital clinical data, according to the different treatment methods were divided into treatment group and control group of 31 patients, of which patients in the control group intravenous ceftazidime, patients in the treatment group intravenous cefoperazone Ketose sulbactam. The clinical efficacy and serum CRP, ALB, PCT, MIF, DD levels before and after treatment were compared between the two groups. Results The total effective rate in the treatment group was 93.55%, significantly higher than that in the control group (80.66%, P <0.05). There was no significant difference in the levels of CRP, ALB, PCT, MIF and DD between the two groups before treatment (P> 0.05). After treatment, CRP, ALB, PCT, MIF, DD in both groups were significantly lower than those before treatment, and the treatment group were significantly lower than the control group, P <0.05. Conclusion Cefoperazone sulbactam treatment of senile pneumonia in patients with serum inflammatory markers, clinical efficacy significantly.