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附子具有强心、抗炎、抗风湿性关节炎等功效,其主要生物活性成分是生物碱。本综述主要介绍附子生物碱的化学成分和质量控制分析方法的研究进展。特别对用于质量控制的分析方法如光谱法、薄层色谱法(TLC)、高效液相色谱法(HPLC)、液-质联用法(LC-MS)、毛细管电泳法(CE)、高速逆流色谱法(HSCCC)进行了详细的论述,为今后附子的研究与应用提供必要的参考。
Aconite with cardiac, anti-inflammatory, rheumatoid arthritis and other effects, the main biological activity of alkaloids. This review mainly introduces the research progress of the chemical constituents and quality control methods of aconite alkaloids. In particular, analytical methods used for quality control such as spectroscopy, thin layer chromatography (TLC), high performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS), capillary electrophoresis (CE) Chromatography (HSCCC) were discussed in detail in order to provide the necessary reference for the future research and application of aconite.