我市钩端螺旋体病(下称钩体病)为黄疸出血群。自1965年在市郊农村首次发生流行以来,每年在郊区农村均有不同程度的流行,而防治对策则是连年接种钩端螺旋体菌苗(下称菌苗),但由于菌苗反应大,群众不愿受种,实施难度大。如何做到菌苗的使用既有效且又合理,为此,我们对菌苗的免疫后效果及其持久性,进行了两年余的血清抗体的动态观察,现报告如下。 Leptospirosis in our city (hereinafter referred to leptospirosis) as jaundice bleeding group. Since the first epidemic occurred in rural areas of the suburbs in 1965, it has been endemic in rural areas in the suburbs for a number of years. However, the prevention and treatment measures have been to inoculate Leptospira bacteria vaccine (hereinafter referred to as bacterin) in successive years. However, Willing to seed, implementation difficult. How to achieve the use of vaccine is both effective and reasonable, for which we have the vaccine after the immune effect and its persistence, carried out more than two years of serum antibody dynamic observation, are as follows.