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目的从血液流变学角度探讨糖尿病及其并发症的发病机制。方法对110例糖尿病患者进行血液流变性检测并与正常对照组作了对照。结果糖尿病患者全血粘度、血浆粘度、红细胞压积等和对照组比较均显著高于对照组(P<0．01)。结论糖尿病患者血液粘度等血液流变性检测指标增高,导致微循环、微血管血流减慢或瘀积,出现微循环障碍。红细胞变形性降低,聚集性增加可能是糖尿病性血管病变的原因之一。
Objective To investigate the pathogenesis of diabetes and its complications from the perspective of hemorheology. Methods 110 cases of diabetic patients were tested for hemorheology and compared with the normal control group. Results The whole blood viscosity, plasma viscosity and hematocrit of diabetic patients were significantly higher than those of the control group (P <0.01). Conclusion The indexes of blood rheology such as blood viscosity of diabetic patients increased, leading to microcirculation, slowing or stasis of microvascular blood flow and microcirculation disturbance. Reduced red cell deformability, increased aggregation may be one of the causes of diabetic vascular disease.