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对１９２例非小细胞肺癌（ＮＳＣＬＣ）接受以放射治疗为主的非手术根治性治疗后，研究有影响的预后因子。方法采用单因素分析和ＣＯＸ多因素模型分析。结果病期早者，鳞癌患者，采用非常规分割放疗者，放疗结束时即期疗效好者，其生存预后好。在各分组中，一、二年生存率为：鳞癌患者８０．３％，４３．６％，非鳞癌患者６２．４％，３２．１％（Ｐ＝０．００５）；Ⅰ＋Ⅱ期８２．４％，６４．２％，Ⅲａ７８．２％，４２．９％，Ⅲｂ６３．８％，２６．８％（Ｐ＝０．００３）；常规放疗６９．３％，２９．０％，超分割７６．４％，４１．４％，加速超分割７８．２％，５４．０％（Ｐ＝０．０１１）；即期疗效完缓解者８１．１％，５７．４％，部分缓解者８０．１％，４２．２％，无变化或进展者５２．５％，１８．３％（Ｐ＜０．００１）。结论病理类型，病期，放射治疗方法，放疗结束时即期疗效为独立的预后因子。
After 192 non-small cell lung cancer (NSCLC) patients received non-surgical radical treatment based on radiation therapy, the impact of prognostic factors was studied. Methods Single factor analysis and COX multi-factor model analysis were used. Results Patients with early stage disease and those with squamous cell carcinoma who were treated with unconventional fractionated radiotherapy had good curative effect at the end of radiotherapy and had a good prognosis. Among the subgroups, the one-year and two-year survival rates were 80.3% in squamous cell carcinoma patients, 43.6%, 62.4% in non-squamous cancer patients, and 32.1% (P=0.005); I+II 82 4%,64.2%,IIIa78.2%,42.9%,IIIb63.8%,26.8%(P=0.003); Conventional radiotherapy 69.3%,29.0%,hyperfractionation 76.4%, 41.4%, accelerated hyperfractionation 78.2%, 54.0% (P=0.011); 81.1%, 57.4% of partial remission of immediate curative effect, partial remission 80 1%, 42.2%, no change or progression were 52.5%, 18.3% (P<0.001). Conclusions The pathological type, stage, radiation therapy, and immediate efficacy at the end of radiotherapy are independent prognostic factors.