【摘 要】
：
目的 总结腹腔镜手术与开放手术在肾上腺疾病外科治疗中的临床经验.方法 回顾性分析486例肾上腺疾病患者的临床资料,其中478例行手术治疗,包括开放手术组318例和腹腔镜手术组
【机 构】
：
上海交通大学医学院附属瑞金医院泌尿外科
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目的 总结腹腔镜手术与开放手术在肾上腺疾病外科治疗中的临床经验.方法 回顾性分析486例肾上腺疾病患者的临床资料,其中478例行手术治疗,包括开放手术组318例和腹腔镜手术组160例.比较两组手术时间、术中出血量、术后肠功能恢复时间、术后疼痛、术后住院天数及手术并发症等方面的差异.结果 开放手术组手术全部成功;腹腔镜手术组154例成功,6例中转开放后成功切除肿瘤.腹腔镜手术组切除肿瘤直径＞6 cm者9例,恶性肿瘤3例,随访3～20个月无复发或转移.两组平均手术时间分别为(112±16)min、(69±10)min,术中平均出血量分别为(286±23)ml、(56±10)ml,术后平均肠功能恢复时间分别为(66±7)h、(24±7)h,术后平均镇痛次数分别为(1.9±0.4)次、(0.5±0.1)次,平均住院天数分别为(10.3±1.1)d、(7.2±0.7)d,并发症发生率分别为40.3%、7.5%,差异有统计学意义(P=0.023,0.007,0.039,O.003,0.029,0.001).结论 腹腔镜肾上腺切除术在手术时间、术中出血量、术后肠功能恢复时间、术后痛疼、住院天数以及并发症发生率等方面均优于传统的开放手术,已成为大部分良性肾上腺疾病治疗的金标准,但在大体积和恶性肿瘤的治疗中仍存在一些限制,正确地选择手术适应证和完善的围手术处理至关重要.
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