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[目的]探讨结肠黑变病(MC)的临床和內镜特点。[方法]对2004年1月～2009年12月经结肠镜检出的145例MC患者的临床资料、内镜下表现及并发息肉、肿瘤的检查结果进行回顾性分析。[结果]6 841例肠镜检查患者中检出MC145例,检出率2.11%;不同性别的检出率差异无统计学意义(P>0.05);>60岁的患者检出率明显高于<60岁患者(P<0.05);多数有便秘和(或)服用泻药病史;MC病变程度与服用泻药时间呈明显正相关(P<0.05)。MC较易合并直径<0.5cm的山田Ⅰ型结肠息肉。[结论]老年人易患MC;MC的发生与便秘和长期服用泻药有关;MC与结肠息肉、肿瘤发生有一定相关性,定期的肠镜随访是非常必要的。
[Objective] To investigate the clinical and endoscopic features of colitis mellitus (MC). [Methods] The clinical data, endoscopic findings and the results of polyps and tumors in 145 MC patients who were diagnosed by colonoscopy from January 2004 to December 2009 were analyzed retrospectively. [Results] The detection rate of MC145 in 6 841 colonoscopy patients was 2.11%. There was no significant difference in the detection rate of different sex (P> 0.05). The detection rate of patients> 60 years old was significantly higher than that of <60 years old (P <0.05). Most patients had constipation and / or taking laxatives. The degree of MC lesions was positively correlated with laxative time (P <0.05). MC more easily combined diameter <0.5cm Yamada type Ⅰ colon polyps. [Conclusion] The elderly are susceptible to MC. The occurrence of MC is related to constipation and long-term use of laxatives. MC has some correlation with colon polyps and tumorigenesis. Regular follow-up of colonoscopy is very necessary.