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目的探讨肝动脉化疗栓塞(TACE)联合射频消融(RFA)治疗原发性肝癌对患者血清尿酸(UA)、白蛋白(ALB)及s Fas水平的影响。方法将原发性肝癌患者220例随机分为观察组和对照组各110例。观察组给予TACE联合RFA治疗,对照组仅给予TACE治疗,分别于治疗前后检测2组患者血清UA、ALB及s Fas水平,并进行比较。结果 2组患者治疗前血清UA、ALB及s Fas水平相近,差异均无统计学意义(P>0.05)。治疗后2组患者血清UA和ALB水平均有所增加,血清s Fas水平均有所降低,且观察组变化幅度明显大于对照组,差异均有统计学意义(P<0.05)。结论 TACE联合RFA治疗原发性肝癌可有效恢复患者血清UA和ALB水平,降低s Fas水平。
Objective To investigate the effect of transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) on the levels of serum uric acid (UA), albumin (ALB) and s Fas in patients with primary liver cancer. Methods 220 patients with primary liver cancer were randomly divided into observation group and control group of 110 cases. The observation group was treated with TACE combined with RFA, while the control group was given TACE only. The levels of serum UA, ALB and sFas in the two groups were measured and compared before and after treatment. Results The levels of serum UA, ALB and s Fas in the two groups before treatment were similar, with no significant difference (P> 0.05). After treatment, serum UA and ALB levels in both groups increased, serum sFas level decreased, and the change range of the observation group was significantly greater than that of the control group, the difference was statistically significant (P <0.05). Conclusion TACE combined with RFA in the treatment of primary hepatocellular carcinoma can effectively restore the level of serum UA and ALB and reduce the level of s Fas.