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川崎病是发生于婴儿的急性发热疾病,可伴多系统血管炎,常与心肌炎和冠状动脉 异常有关,其最重要的并发症是心脏受累。起病第一周应用单次大剂量IVGG(静脉注射丙球)2.0g/kg可明显降低心血管并发症。 心脏肌钙蛋白I(Cardiac troponin I,简称cTnI)只有在心肌细胞损害后才表达,该文观察了急性期川崎病人血清cTnI的水平,(可作为心肌炎和心肌细胞损伤的早期血清学检测指标)。
Kawasaki disease occurs in infants with acute febrile illness and may be associated with multiple systemic vasculitis, often associated with myocarditis and coronary artery abnormalities. The most important complication is heart involvement. In the first week of onset, a single high dose of IVGG (intravenous injection of corticosteroid) 2.0g / kg significantly reduced cardiovascular complications. Cardiac troponin I (cTnI) is expressed only after cardiomyocyte damage. This study examined the serum level of cTnI in patients with acute Kawasaki disease, which can be used as an early serological marker of myocarditis and cardiomyocyte injury. .