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目的探讨晚间持续应用Bi PAP呼吸机辅助呼吸治疗II型呼吸衰竭患者的疗效。方法选择50例我院收治的II型呼吸衰竭患者,行常规药物治疗,并采用Bi PAP呼吸机辅助治疗。按使用呼吸机的不同时间点分为B组和A组,其中B组24例,白天使用呼吸机,A组26例,晚间使用呼吸机。对两组患者治疗前后的各血气指标、生命体征参数以及临床疗效进行分析和对比。结果 1两组患者治疗后各时间点的p H值以及血氧分压均较治疗前均有明显上升,而二氧化碳分压均较治疗前有显著下降,差异具有统计学意义(均P<0.05);且A组患者治疗后p H值、二氧化碳分压、血氧分压均显著由于B组,差异具有统计学意义(均P<0.001);2两组患者治疗后各时间点的心率明显低于治疗前,呈下降趋势,而呼吸频率和平均动脉压则在治疗后24h出现上升,在治疗后72h和10d反而下降,差异具有统计学意义(均P<0.05);且A组患者治疗后各生命体征指标明显比B组要好,差异具有统计学意义(均P<0.001);3两组患者治疗后,A组患者的治疗效果明显优于B组,差异具有统计学意义(P<0.001)。结论对ICU监护的II型呼吸衰竭患者行晚间持续应用Bi PAP呼吸机辅助呼吸治疗可明显改善患者血气、生命体征,有效提高治疗的效果,值得临床借鉴和推广。
Objective To investigate the effect of continuous application of Bi PAP ventilator assisted breathing in patients with type II respiratory failure in the evening. Methods Fifty patients with type II respiratory failure admitted to our hospital underwent routine medical treatment and assisted by Bi PAP ventilator. According to the use of ventilator at different time points are divided into group B and group A, including 24 cases in group B, ventilator during daytime, group A 26 cases, night use ventilator. The two groups of patients before and after treatment of blood gas indicators, vital signs and clinical efficacy analysis and comparison. Results 1 After treatment, the p H value and the partial pressure of blood oxygen in both groups were significantly increased compared with those before treatment, while the partial pressure of carbon dioxide decreased significantly compared with that before treatment (all P <0.05 ). After treatment, the values of p H, carbon dioxide partial pressure and partial pressure of oxygen were significantly different in group A as compared with those in group B (all P <0.001). The heart rate of each group was significantly higher after treatment The respiratory rate and mean arterial pressure increased at 24h after treatment, but decreased at 72h and 10d after treatment, the difference was statistically significant (all P <0.05); and the treatment of patients in group A The indexes of vital signs in each group were significantly better than those in group B (all P <0.001). 3 After treatment, the treatment effect of group A was better than group B, the difference was statistically significant (P < 0.001). Conclusions Continuous use of Bi PAP ventilator-assisted respiration therapy in ICU-monitored patients with type II respiratory failure can significantly improve the blood gas and vital signs of patients and effectively improve the therapeutic effect, which is worthy of clinical reference and promotion.