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目的:分析并研究新生儿感染性疾病患儿降钙素原水平的变化情况,从而确定降钙素原在疾病诊断中的价值,为临床提供诊断依据。方法:选取2013年10月~2014年8月该院收治的新生儿感染性疾病患儿96例为试验组,另选取同期体检健康的新生儿96例为对照组,测定并对比分析两组新生儿体内降钙素原水平。结果:试验组阳性患儿87例(90.62%),阴性患儿9例(9.38%);对照组阳性患儿3例(3.13%),阴性患儿93例(96.87%)。两组比较差异有统计学意义(P<0.05)。试验组治疗后血清降钙素原水平明显降低,与治疗前比较差异有统计学意义(P<0.05)。结论:降钙素原水平变化能够准确地反映出新生儿是否感染以及感染的程度,对感染性疾病诊断具有重要的临床意义,诊断的灵敏性和特异性极高,值得在临床上广泛应用。
Objective: To analyze and study the changes of procalcitonin in neonates with infectious diseases so as to determine the value of procalcitonin in the diagnosis of the disease and provide the basis for clinical diagnosis. Methods: Ninety-six children with neonatal infectious diseases admitted to our hospital from October 2013 to August 2014 were selected as the experimental group. Another 96 healthy newborn infants were selected as the control group during the same period. Procalcitonin levels in children. Results: There were 87 cases (90.62%) in the test group and 9 cases (9.38%) in the negative group. There were 3 cases (3.13%) in the control group and 93 cases (96.87%) in the negative group. The difference between the two groups was statistically significant (P <0.05). The level of serum procalcitonin in experimental group was significantly lower than that before treatment (P <0.05). CONCLUSION: The change of procalcitonin level can accurately reflect the degree of neonatal infection and infection. It has important clinical significance for the diagnosis of infectious diseases, and its sensitivity and specificity are very high. It is worth widely used in clinic.