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目的了解婴幼儿和学龄前儿童的呼出气一氧化氮(FeNO)检测水平。方法选取1 450例儿童,年龄3 d至6岁,男性935例、女性515例,检测FeNO水平,比较不同性别、不同年龄段儿童的FeNO水平。结果 1 450名婴幼儿和学龄前儿童FeNO水平为(11.14±6.18)ppb,95%CI[10.91,11.38];男性FeNO水平为(10.90±5.55)ppb,低于女性的(11.54±7.08)ppb(P<0.05)。各年龄段儿童FeNO水平比较,差异有统计学意义(P<0.05),其中>2~3岁儿童的FeNO水平最高,其次为新生儿。结论婴幼儿及学龄前儿童FeNO水平波动范围平稳,不同年龄段儿童FeNO水平不同,年龄可能是影响FeNO水平的重要因素之一。
Objective To understand the detection of exhaled nitric oxide (FeNO) in infants and preschool children. Methods A total of 1 450 children aged 3 to 6 years were enrolled in this study. There were 935 males and 515 females. The level of FeNO was detected and the levels of FeNO in different gender and age groups were compared. Results FeNO level was (11.14 ± 6.18) ppb and 95% CI in 1 450 infants and preschool children, respectively (10.91 ± 5.55) ppb and (11.54 ± 7.08) ppb in females (P <0.05). FeNO levels in children of all ages had statistical significance (P <0.05), among which, children aged> 2-3 yielded the highest levels of FeNO, followed by neonates. Conclusion The range of FeNO level in infants and preschool children is stable. FeNO level is different in children of different ages, and the age may be one of the important factors that affect FeNO level.