血管紧张素转换酶在血压调节中扮演重要角色。降血压肽通过抑制血管紧张素Ⅰ向血管紧张素Ⅱ的转化以及阻止ACE使激肽失活而起降血压的作用。利用某些蛋白酶对食品蛋白质的定位水解而可产生具有降血压活性的短肽。降血压肽的分离提取是降血压肽生产的难点所在。综述降血压肽的作用机制及其酶法制备和分离提取的研究进展。 Angiotensin-converting enzyme plays an important role in blood pressure regulation. Antihypertensive peptides play a role in lowering blood pressure by inhibiting the conversion of angiotensin I to angiotensin II and preventing the inactivation of kinins by ACE. The use of certain proteases for the localized hydrolysis of food proteins can produce hypotensive activity of short peptides. Isolation and extraction of hypotensive peptide is the difficulty of producing hypotensive peptide. The mechanism of antihypertensive peptide and its research progress in enzymatic preparation and separation and extraction were summarized.