[目的]探讨内镜介入和中药治疗疣状胃炎的临床价值。[方法]经胃镜诊断明确的220例疣状胃炎患者随机分为西药组和中西药组,各110例,两组均采用内镜介入方法,共治疗疣状隆起病变536枚,术后分别给予西药和中西药结合治疗,1~2个月后观察镜下病变形态学变化、幽门螺杆菌(Hp)转阴及腹痛、烧心、反酸等症状变化。[结果]全部病例治疗后疣状隆起消失率达94.7%,西药组及中西药组分别为93.6%及94.6%,Hp转阴率分别为93.6%及95.5%,两组疗效比较差异无统计学意义(P>0.05)。临床症状缓解率西药组为78.6%,中西药组为91.8%,中西药组明显优于西药组(P<0.05)。[结论]疣状胃炎采用内镜介入方法治疗安全、有效、可靠;在改善临床症状方面,中西药组明显优于西药组。 [Objective] To investigate the clinical value of endoscopic intervention and traditional Chinese medicine in the treatment of verrucous gastritis. [Methods] 220 cases of verrucous gastritis diagnosed by gastroscopy were randomly divided into western medicine group and western medicine group, with 110 cases in each group. Both groups adopted endoscopic interventional method to treat 536 verrucous bulge lesions and were given postoperative Western medicine and Western medicine treatment, 1 to 2 months after the observation of microscopic changes in morphology, Helicobacter pylori (Hp) and abdominal pain, heartburn, acid reflux and other symptoms. [Results] The disappearance rate of verrucous bulge was 94.7% in all cases, 93.6% and 94.6% in western medicine group and western medicine group respectively, and the negative conversion rates of Hp were 93.6% and 95.5% respectively. There was no significant difference in the curative effect between the two groups Significance (P> 0.05). The rate of clinical symptom relief was 78.6% in Western medicine group and 91.8% in Western medicine group, which was significantly better in Western medicine group than Western medicine group (P <0.05). [Conclusion] The treatment of verrucous gastritis by endoscopic intervention is safe, effective and reliable. Compared with western medicine group, Chinese and western medicine group is significantly better in improving clinical symptoms.