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目前WHO推荐的治疗血吸虫病的药物只有吡喹酮(Pra)和奥杀尼喳(Oxa)两种[1],Oxa因仅对曼氏血吸虫病有效,又可诱导抗性,且其价格较Pra贵3~10倍,故临床使用在逐步减少,在血吸虫病防治中的地位远不如Pra重要。Pra不但高效低毒,而且对人体5种血吸虫病均有效,自70年代中
Currently, only the drugs recommended by the WHO for the treatment of schistosomiasis are praziquantel (Pra) and oxacillin (Oxa) [1]. Oxa, which is effective only against Schistosoma mansoni and induces resistance, is more expensive Pra expensive 3 to 10 times, so the clinical use is gradually reduced, the status of prevention and treatment of schistosomiasis is far less important than Pra. Pra not only high efficiency and low toxicity, but also on the human body 5 kinds of schistosomiasis are effective since the 70s