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为探讨＋Ｇｚ重复暴露对脑皮层神经元的损害及其机理，用光镜与电镜对＋１０Ｇｚ／３ｍｉｎ重复暴露三次后不同时间大鼠脑皮层结构进行了定性观察。结果表明：①光镜下可见，＋Ｇｚ重复暴露三次后大鼠顶叶皮层少数神经元表现为缺血性改变，暴露后２４ｈ即已基本恢复正常。②电镜下可见，＋Ｇｚ重复暴露三次后大鼠脑皮层少数锥体细胞线粒体肿胀、嵴模糊不清；散在锥体细胞变性，内质网、核糖体减少，溶酶体增多；毛细血管内皮细胞伸向管腔的突起增多。暴露后２４ｈ皮层神经元超微结构则基本恢复正常。提示，＋１０Ｇｚ／３ｍｉｎ重复暴露引起的大鼠脑皮层神经元损害是可逆的。其可能主要与＋Ｇｚ引起的脑缺血及脑内应力变化等有关。
In order to investigate the damage and mechanism of cortical neurons with + Gz repeated exposure, the cerebral cortical structures of rat cortex at different times after +10 Gz / 3 min exposure were observed by light microscope and electron microscope. The results showed that: ① Under the light microscope, a few neurons in the parietal cortex of the rats showed ischemic changes after repeated exposures to + Gz for three times and returned to normal after 24 hours of exposure. ② Electron microscopy showed that after repeated exposure of + Gz for three times, mitochondria of a few pyramidal cells in the cerebral cortex of the rats were swollen and the cristae were blurred. The degeneration of pyramidal cells, the decrease of the endoplasmic reticulum and the ribosome, and the increase of lysosomes in the scattered pyramidal cells of the rat cortex; Protrusion to the lumen increased. The ultrastructure of cortical neurons returned to normal after 24h exposure. Tip, + 10Gz / 3min repeated exposure caused by cerebral cortex neuronal damage is reversible. It may be mainly related to + Gz induced cerebral ischemia and changes in brain stress.