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目的:了解七叶皂苷钠注射液在神经科应用规律和特点,指导临床合理用药。方法:全面检索七叶皂苷钠注射液近几年在神经科临床应用的文献研究资料,将其在脑炎、脑血管意外、中毒性脑病、急性脑梗死、格林-巴利综合征和面神经炎等神经内科疾病,以及在脑外伤、颅高压、颅脑损伤术后脑肿胀、脊髓缺血损伤等神经外科治疗中的作用和效果进行简单汇总。结果:七叶皂苷钠注射液对脑组织具有明显的抗炎、抗渗出、抗水肿和增强血管舒张等方面的药理作用,尤其对改善轻中度脑水肿效果显著,疗效确切。结论:七叶皂苷钠注射液用于神经科相关疾病的治疗,是一种安全、有效的药物,应用过程中应控制给药剂量,同时密切监测不良反应。
Objective: To understand the application rules and characteristics of sodium aescinate in neurology, to guide clinical rational drug use. Methods: A comprehensive literature search on the clinical application of sodium aescinate in neurology in recent years was conducted, and the data were collected in encephalitis, cerebrovascular accident, toxic encephalopathy, acute cerebral infarction, Guillain-Barre syndrome and facial neuritis And other neurological diseases, as well as in brain trauma, intracranial hypertension, brain swelling after traumatic brain injury, spinal cord injury and other neurosurgical treatment of the role and effect of a simple summary. Results: Sodium aescinate injection had obvious anti-inflammatory, anti-exudation, anti-edema and vasodilatation effects on brain tissue, especially for improving mild to moderate cerebral edema. Conclusion: Sodium aescinate injection is a safe and effective drug for the treatment of diseases related to neurology. The dosage of sodium aescinate should be controlled in the course of application, and the adverse reactions should be closely monitored.