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目的:探讨间歇性管饲结合高压氧治疗对脑卒中吞咽障碍患者的临床疗效。方法:选取2017年11月至2020年1月粤北人民医院康复医学科脑卒中后吞咽功能障碍住院患者93例作为研究对象。按照数字表法随机分为3组，每组31例，A组为间歇性管饲＋高压氧组，B组为高压氧组，C组为间歇性管饲组。所有患者均接受常规脑卒中药物治疗，功能训练包括偏瘫肢体综合训练、作业治疗、物理因子治疗、日常生活活动能力训练等。对所有患者采用干预前后改良Mann吞咽能力量表(MMASA)、标准吞咽功能评定量表(SSA)、功能性进口进食量表(FOIS)及Fugl-Meyer运动功能量表进行评估。结果:3组患者MMASA、SSA和FOIS评分在干预前后比较，差异均有统计学意义(n P<0.05)。3组患者治疗后MMASA、SSA和FOIS评分比较，差异有统计学意义(n P<0.05)。治疗后组间比较，A组患者较B、C组吞咽障碍改善更明显(n P<0.05)。3组患者干预后Fugl-Meyer运动功能评分较干预前有明显改善(n P<0.05)。与C组比较，治疗后A、B组Fugl-Meyer运动功能评分均有明显改善(n P<0.05)。3组患者吸入性肺炎发生率分别为6.1%、19.3%和38.7%。A组吸入性肺炎发生率明显低于其他2组(n P<0.05)。n 结论:脑卒中后间歇性管饲联合高压氧治疗可以更好地改善患者吞咽功能，提高运动能力，降低吸入性肺炎的发生率。“,”Objective:To study the clinical effect of intermittence oro-esophageal tube feeding (IOE) combined with hyperbaric oxygen (HBO) therapy on patients with dysphagia after stroke.Methods:A total of 93 patients with dysphagia after stroke admitted to the Department of Rehabilitation Medicine of Yue Bei People’s Hospital from November 2017 to January 2020 were selected as the subjects of the study and randomly divided into 3 groups (n n=31) according to random number table method: group A (IOE+ HBO group), group B (HBO group), and group C (IOE group). All patients received conventional stroke drug therapy and functional training, including hemiplegic limb comprehensive training, exercise therapy, physical factor therapy, and daily activity training. After 4 weeks, all patients were evaluated by the modified mann assessment of swallowing ability (MMASA), standardized swallowing assessment (SSA), functional oral intake scale (FOIS), and Fugl-Meyer assessment (FMA) for motor functioning on the changes before and after intervention.n Results:The scores of MMASA, SSA, and FOIS in the 3 groups were compared before and after intervention, and the differences were statistically significant (n P<0.05). Then the scores of MMASA, SSA, and FOIS of the 3 groups were compared with each other after treatment, and the differences were statistically significant (n P<0.05). After treatment, the improvement of dysphagia in the group A was more obvious than those in the group B and C (n P<0.05). The FMA results after intervention were significantly improved in the 3 groups compared with those before intervention (n P<0.05). The FMA results after treatment in the group A and B were significantly improved than that in the group C, respectively (n P<0.05). The incidence of aspiration pneumonia in each group was 6.1%, 19.3%, and 38.7%, respectively. The incidence of aspiration pneumonia in the group A was significantly lower than those in the other two groups (n P<0.05).n Conclusion:Intermittent oro-esophageal tube feeding combined with hyperbaric oxygen therapy after stroke can improve dysphagia and the patient’s motor functioning, and reduce the incidence of aspiration pneumonia.