血管生成是指已经存在于组织的成熟血管内皮细胞,通过增殖游走,以出芽或者嵌入的方式形成新生血管的过程。在胚胎形成、女性月经期子宫内膜的周期性重建、伤口愈合及组织器官慢性缺血缺氧等条件下,该过程的发生对机体的生长发育及生存有重要意义。然而,当恶性肿瘤发生时,血管生 Angiogenesis refers to the process of forming neovascularization by budding or embedding through the proliferation of vascular endothelial cells already existing in the tissue. Under the conditions of embryogenesis, periodic reconstruction of female endometrium during menstruation, wound healing and chronic hypoxia of tissues and organs, the occurrence of this process is of great significance to the growth and survival of the body. However, when malignant tumors occur, angiogenesis