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目的探讨多瑞吉(芬太尼透皮贴剂)、美施康定(硫酸吗啡缓释片)以及奥施康定(盐酸羟考酮缓释片)在晚期癌痛患者治疗中的效果以及护理方法。方法 120例晚期癌痛患者,根据止痛治疗方式不同将其分为多瑞吉组(给予多瑞吉治疗)、美施康定组(给予美施康定治疗)和奥施康定组(给予奥施康定治疗),各40例。比较三组患者治疗后的止痛缓解疗效以及不良反应发生情况。结果三组患者止痛总有效率分别为92.5%、90.0%、95.0%,比较差异无统计学意义(P>0.05)。多瑞吉组患者胃肠道反应、排尿困难发生率低于美施康定组和奥施康定组,皮肤红肿瘙痒发生率高于美施康定组和奥施康定组(P<0.05);三组呼吸抑制、中枢抑制反应发生率比较差异无统计学意义(P>0.05)。结论医疗人员要以个性化选择用药的方式对待晚期癌痛患者,密切关注治疗情况,尽可能帮助患者解除痛楚,消除不良反应,以提高生活质量。
Objective To investigate the effect of Du Ruiji (fentanyl transdermal patch), mesylate (morphine sulfate sustained-release tablets) and oxycodone hydrochloride (oxycodone hydrochloride sustained-release tablets) in the treatment of patients with advanced cancer pain and nursing methods . Methods One hundred and twenty patients with advanced cancer pain were divided into two groups according to different analgesic methods: treatment with Duoritai, treatment with Meishenkang, Treatment), 40 cases each. Three groups of patients after treatment to relieve pain relief efficacy and adverse reactions. Results The total effective rates of analgesic in the three groups were 92.5%, 90.0% and 95.0% respectively, with no significant difference (P> 0.05). The incidence of gastrointestinal reaction and dysuria in the Duoerji group was lower than that in the Mischistogen group and Oxaliplatin group, and the incidence of itching in the skin was higher than that in the Mischudan and Oxycodin groups (P <0.05) Respiratory depression, central suppression reaction was no significant difference in the incidence (P> 0.05). Conclusion Medical staff should treat patients with advanced cancer with personalized choice of medication, pay close attention to the treatment, and try their best to relieve the pain and eliminate the adverse reactions so as to improve the quality of life.