近十年来,随着人们对一氧化氮(NO)[1]研究的不断深入,作为NO合成前体L-精氨酸(L-Arg)[2],在心血管疾病的发展进程中所起的作用正日益受到科学工作者的广泛关注。1　L-Arg-NO系统Furchgott和Zawadski于1980年首次证实在内皮细胞存在的情况下,由乙酰胆碱(Ach)介导的游离动脉可引? In the last decade, with the continuous research on nitric oxide (NO) [1], L-arginine (L-Arg), a precursor of NO synthesis, has been developed in the process of cardiovascular disease The role of scientists is increasingly widespread concern. 1 L-Arg-NO system Furchgott and Zawadski first demonstrated in 1980 that in the presence of endothelial cells, free artery mediated by acetylcholine (Ach)