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目的了解河北省保定市社区中老年居民糖尿病前期(IGR)患病情况及其危险因素。方法随机整群抽取保定市社区≥45岁居民3 250人为筛查对象。末梢血血糖≥5.1 mmol/L者进行75 g口服葡萄糖耐量试验。结果标化患病率分别为IGR 7.4%、DM 20.0%;IFG、IGT及IFG/IGT标化患病率分别为1.6%、6.5%和1.2%;随着年龄增加,IGR患病率增加,年龄与IGR呈正趋势(χ2趋势=22.3047,P<0.05),IGR/DM的比值在45～54岁组最高(0.49);多因素非条件Logistic回归分析表明,常食水果(OR=0.704,95%CI=0.625～0.796)和锻炼(OR=0.222,95%CI=0.171～0.671)为保护性因素;紧张情绪(OR=1.465,95%CI=1.161～1.849)、中心性肥胖(OR=2.185,95%CI=1.729～2.762)、高脂血症(OR=1.663,95%CI=1.339～1.992)和DM家族史(OR=2.009,95%CI=1.640～2.471)为危险性因素。结论保定市中老年社区人群IGR患病率处于中等水平,紧张情绪、中心性肥胖、高脂血症和DM家族史是主要危险因素。
Objective To investigate the prevalence of pre-diabetes mellitus (IGR) and its risk factors in middle-aged and elderly residents in Baoding City, Hebei Province. Methods A random cluster of 3 250 people aged ≥ 45 in Baoding community were selected as screening subjects. Peripheral blood glucose ≥ 5.1 mmol / L were 75 g oral glucose tolerance test. Results The standardized rates of IGR were 7.4% and 20.0%, respectively. The prevalences of IFG, IGT and IFG / IGT were 1.6%, 6.5% and 1.2% respectively. The prevalence of IGR increased with age, The ratio of IGR / DM was the highest (0.49) in the 45-54 age group. Logistic regression analysis showed that there was a significant positive correlation between age and IGR (χ2 trend = 22.3047, P <0.05) (OR = 1.465, 95% CI = 1.161-1.849) and central obesity (OR = 2.185, CI = 0.625-0.796) and exercise (OR = 0.222, 95% CI = 0.171-0.671) (OR = 1.663, 95% CI = 1.339-1.992) and DM family history (OR = 2.009, 95% CI = 1.640-2.471) were risk factors. Conclusion The prevalence of IGR in middle-aged and elderly people in Baoding is at a moderate level. Tension, central obesity, hyperlipidemia and DM family history are the major risk factors.