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片剂里的药物要在消化道内能溶解或崩解才能起到治疗作用。有些药物需要在胃液中吸收才能起到治疗效果,因此制成的片剂亦需要在胃液中及时崩解或溶解;有些药物需要在肠液中作用取得治疗效果,所以制成的片剂必需在胃液中不崩解,到肠液中才崩解或溶解。所以崩解度是片剂质量的重要要求之一,各国药典对於片剂都规定有崩解度的检查与崩解时限。我们药典规定的崩解时限是15分钟以内,是每片在约45毫升的水中测定的。在此水量能够溶解的药物是不是都能在15分钟内达到溶
Medication in tablets should be able to dissolve or disintegrate in the digestive tract to play a therapeutic role. Some drugs need to be absorbed in the gastric juice in order to play a therapeutic effect, so the resulting tablets also need to collapse or dissolve in time in the gastric juice; some drugs need to obtain the effect of treatment in the intestinal fluid, the resulting tablets must be in the gastric juice In the collapse does not collapse until the collapse of intestinal fluid or dissolved. Therefore, the degree of disintegration is one of the important requirements of the tablet quality, the national pharmacopoeia for tablets are provided with a disintegration degree of inspection and disintegration time limit. Our Pharmacopoeia Disintegration Limits are within 15 minutes and are measured in about 45 ml of water per tablet. In this water can dissolve the drug can not be dissolved in 15 minutes