本文要点:骨疼—骨髓坏死—链球菌。作者报告一例,且结合文献,加以阐明。女,8岁,突然高热,右膝关节持续剧痛。同时右脚背上有一谷粒大小疖,肝脾轻度肿大。白细胞(2500/μl)和血小板(78.000/μl)减少,疑诊为白血病而收住院。抗链球菌溶血素效价600μ/ml。不同时期三次血培养和一次骨髓培养,都有A型链球菌生长。骨髓穿刺涂片检查:极少巨核细胞。多数细胞具有浓染的细胞核,没有胞浆或细胞细致 This article highlights: bone pain - bone marrow necrosis - Streptococcus. The author reports one case, and combined with the literature to clarify. Female, 8 years old, suddenly hot, severe pain in right knee joint. At the same time there is a grain size on the right foot 疖, liver and spleen mild swelling. White blood cells (2500 / μl) and platelets (78.000 / μl) decreased, admitted to leukemia hospitalization. Anti-streptolysin titer 600 μ / ml. Three times in different periods of blood culture and a bone marrow culture, there are Streptococcus A-type growth. Bone marrow biopsy: very few megakaryocytes. Most cells have stained nuclei, lacking cytoplasm or cells