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目的分析解放军307医院清洁手术预防性使用抗菌药物情况,包括使用率、用药时机、用药时长等指标的变化趋势,为建立抗菌药物合理使用的长效机制提供参考。方法提取HIS系统中2009年1月至2014年5月期间该医院外科清洁手术患者抗菌药物使用记录,计算相关指标进行分析。结果清洁手术抗菌药物预防使用率从等级医院评审前的70%下降到50%,髋关节置换术、膝关节手术的使用率也呈稳定下降趋势;但子宫肌瘤切除术下降至40%后急剧反弹至80%,其使用时长从之前的2.47 d缩短至0.16 d,反映其用药策略发生了较大变化。结论随着等级医院迎检工作的开展,医院采取了一系列合理使用抗菌药物的举措,使各项指标均有明显改善,并呈持续改进的趋势,反映了控制措施得力,收效明显。
OBJECTIVE: To analyze the trend of preventive use of antibacterials in the operation of the 307 Hospital of People’s Liberation Army (PLA 307), including the usage rate, the timing of medication and the duration of medication, and provide a reference for establishing a long-term mechanism for rational use of antimicrobial agents. Methods The records of antimicrobial use in patients undergoing surgical cleansing in the hospital from January 2009 to May 2014 were extracted and the relevant indexes were calculated and analyzed. Results The rate of preventive use of antibacterials for clean operation decreased from 70% before grade hospitals to 50%, and the usage rate of total hip arthroplasty and knee arthroplasty decreased steadily. However, the rate of myomectomy decreased sharply to 40% Rebounded to 80%, the use of time from the previous 2.47 d shortened to 0.16 d, reflecting the medication strategy has undergone major changes. Conclusion With the progress of the welcome examination at the level hospitals, the hospital adopted a series of measures to rationalize the use of antimicrobial agents, which have significantly improved various indicators and showed a continuous improvement trend, reflecting the effective control measures and obvious benefits.