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为了研究长期低剂量内照射对人类遗传指标的影响，采用人体外周血淋巴细胞微核测定法，对长期饮用高本底放射性饮水的人群进行了微核测定。同时，以此高放射性水饲养小鼠，５０天后做小鼠骨髓嗜多染红细胞微核测试。结果显示暴露组人群的微核率显著高于对照组（Ｐ＜０．０１）；动物实验所得处理组微核率与对照组无显著差异（Ｐ＞０．０５）。文中分析了产生这种现象的原因，并认为有必要对暴露人群做前瞻性调查，以寻找剂量－效应关系，为高放射性核素饮用水的安全性评价提供科学依据
In order to study the effects of long-term low-dose internal irradiation on human genetic markers, human peripheral blood lymphocyte micronucleus assay was used to determine micronuclei in long-term high-drinking radioactive drinking water. At the same time, mice were bred with this high radioactive water and mouse bone marrow polychromatic erythrocytes micronucleus test was performed after 50 days. The results showed that the micronucleus rate of the exposed group was significantly higher than that of the control group (P <0.01). There was no significant difference between the treated group and the control group (P> 0.05). This article analyzes the reasons for this phenomenon and considers it necessary to do a prospective investigation of exposed populations in search of dose-response relationships to provide a scientific basis for the safety assessment of high radionuclide drinking water