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实验中用Ｂｅａｇｌｅ狗１０只，以０．０２４７～０．０２７８Ｃ·ｋｇ－１·ｍｉｎ－１照射量率，全身照射６．５Ｇｙ，分３组：第１组３只，作为对照，不给任何治疗，照射后全部死亡，平均活存７．５天。第２组４只，移植性别相反的同种血造血干细胞。供受体混合淋巴细胞培养刺激指数小于０．６９，红细胞交叉凝集试验阴性，未在体外去除供体血细胞中的Ｔ淋巴细胞。结果表明，照射后１１，２０和２６天检查性染色体，均为供体核型。４只狗死于严重ＧＶＨＤ，平均活存４ｌ．６天。第３组３只，移植去除Ｔ淋巴细胞的同种血干细胞，２只死亡，１只发生轻度ＧＶＨＤ，长期活存４年以上。
In the experiment, 10 Beagle dogs were used to irradiate the whole body with a dose of 0.0247 ~ 0.0278C · kg-1 · min-1, and the whole body was irradiated with a dose of 6.5Gy, and divided into 3 groups: group 1, group 3, After treatment, all died after irradiation, with an average survival of 7.5 days. The second group of 4, allograft transplanted blood of the same type of hematopoietic stem cells. Recipient mixed lymphocyte culture stimulation index was less than 0.69, red blood cell cross-agglutination test negative, did not remove T lymphocytes in donor blood cells in vitro. The results showed that 11, 20 and 26 days after irradiation sex chromosomes, are donor karyotype. Four dogs died of severe GVHD with an average survival of 4l. 6 days. In group 3, 3 allogeneic stem cells were removed from T lymphocytes, 2 died, 1 had mild GVHD, and had long-term survival of more than 4 years.