巯甲丙脯酸为血管紧张素转换酶抑制剂,此药已成功地应用于治疗高血压和难治性心衰,但可导致病人的血清钾上升。因慢性肾功能衰竭作血透治疗的患者可能有高钾血症的存在,如果同期采用巯甲丙脯酸,更应注意高钾血这个问题。本文对76个接受规律性血透治疗的晚期慢性肾衰患者进行了研究。每次透析历时4小时,每周3次,用铜酚膜,透析液含钾1.5mEq/L,钠137mEgq/L。持续6个月时间,在透析前每月采集血浆标本2次,测钾、钠、尿素和肌酐。将76例分为三组。34例(45％)血压正常者为第一组,26例(34％)采用甲基多巴,肼苯哒嗪等常规抗高血压药物治疗为第二 Captopril is an angiotensin-converting enzyme inhibitor that has been successfully used in the treatment of high blood pressure and refractory heart failure but can lead to elevated serum potassium in patients. Hemodialysis patients with chronic renal failure may have the presence of hyperkalemia, if the same period with captopril, should pay more attention to the issue of high blood potassium. In this paper, 76 patients with advanced chronic renal failure undergoing regular hemodialysis were studied. Each dialysis lasted 4 hours, 3 times a week, with copper phenol membrane, dialysate potassium 1.5mEq / L, sodium 137mEgq / L. For 6 months, plasma samples were collected twice a month before dialysis to measure potassium, sodium, urea and creatinine. The 76 cases were divided into three groups. Twenty-four patients (45%) had normotensive patients in the first group and 26 patients (34%) received conventional antihypertensive drugs such as methyldopa and hydralazine for the second