论文部分内容阅读
目的对保定市手足口病伴脱甲症的病例进行流行病学特征分析,为制定防控措施提供科学依据。方法对保定市2015年1月-2016年5月手足口病确诊病例进行随访,从发病后连续观察3个月,筛选脱甲病例并对其流行病学特征进行分析。分类资料利用SPSS 11.5软件进行卡方检验。结果在684份肠道病毒检测阳性的手足口病确诊病例中143例出现了脱甲症状,脱甲发生率为20.91%。脱甲发生与手足口病患者的年龄、性别、城乡分布以及发病月份无关,但北部和中部脱甲发生率(25.12%、22.87%)显著高于南部(14.22%,P<0.05)。肠道病毒EV71(EV71)、柯萨奇病毒A16型(Cox A16)、柯萨奇病毒A6(CoxA6)以及其他肠道病毒所致的手足口病均出现脱甲现象,其中以CoxA6型手足口病脱甲发生率最高,为44.64%。结论 2015-2016年保定市脱甲症病例集中在北部和中部,CoxA6为主要病原。
Objective To analyze the epidemiological characteristics of hand-foot-mouth disease with demethylation in Baoding, and provide a scientific basis for making prevention and control measures. Methods The confirmed cases of HFMD in Baoding City from January 2015 to May 2016 were followed up for 3 months after onset. The cases of dementia were screened and their epidemiological characteristics were analyzed. Classification data using SPSS 11.5 software for chi-square test. Results Of the 684 confirmed cases of enterovirus-positive hand-foot-mouth disease, 143 cases had dementia and the incidence of dementia was 20.91%. The incidence of dementia was not related to the age, sex, urban-rural distribution and onset of HFMD among patients with hand-foot-mouth disease. However, the incidence of dementia in northern and central regions was significantly higher than that in the south (25.12% and 22.87%, P <0.05). Dementia was observed in enterovirus EV71 (EV71), Cox A16 (Cox A16), CoxA6 and other enteroviral hand-foot-and-mouth disease, among which CoxA6 type hand-foot-mouth The highest incidence of disease and dementia was 44.64%. Conclusion The cases of demethylation in Baoding City in 2015-2016 are concentrated in the northern and central areas with CoxA6 as the main pathogen.