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本文对45例肾脏病及5例原发性高血压进行了肾排钠分数(FE_(Na))的测定。结果:13例慢性肾功衰竭中11例FE_(Na)>5,最高可达30,平均为11.4。3例急性肾炎FE_(Na)皆<1;12例肾病综合征FE_(Na)4例>4,6例<1,2例>1<3。5例原发性高血压中,4例FE_(Na)>1。其结论认为慢性肾衰,无论有无水肿,FE_(Na)皆明显增高;急性肾炎FE_(Na)无明显增高;肾病综合征FE_(Na)增高可能提示为Ⅱ型肾病综合征;原发性高血压无可觉察的肾功能受累者,其FE_(Na)增高,可能提示为高血压导致肾功能受累时的早期改变,或者表明原发性高血压发病过程中存在着潴钠导致的利钠激素释放增多。
In this paper, 45 cases of kidney disease and 5 cases of essential hypertension were measured renal sodium fraction (FE Na). Results: Of the 13 patients with chronic renal failure, 11 were FE_ (Na)> 5, up to 30, with an average of 11.4.3 cases of acute nephritis with FE_ (Na) <1; 12 cases of nephrotic syndrome FE_ (Na) > 4,6 cases <1, 2 cases> 1 <3.5 cases of essential hypertension, 4 cases of FE Na> 1. The conclusion is that chronic renal failure, with or without edema, FE_ (Na) were significantly increased; acute nephritis FE_ (Na) was no significant increase; nephrotic syndrome FE_ (Na) increased may suggest type Ⅱ nephrotic syndrome; Hypertension with impaired renal function impaired, FE_ (Na) increased, may suggest early changes in renal function due to hypertension or the presence of sodium in the pathogenesis of essential hypertension sodium Hormone release increased.